The National Institutes of Health’s (NIH’s) All of Us Research Program is building one of the largest biomedical data resources of its kind with health data from a diverse group of participants across the United States, including people and communities who have been left out of medical research in the past.1 Data include biological factors and social determinants of health on a large, inclusive scale that tracks participants as they move, age, and grow (longitudinal study design).  

Data sources include: 

• Electronic Health Records (EHR) standardized using the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) 

• Biosamples and bioassays from blood, saliva, and/or urine samples 

• Survey responses on identities and backgrounds, overall health, lifestyles, medical histories, healthcare access, experiences with COVID-19, and more 

• Physical measurements when joining program 

• Heart rate, physical activity, and sleep as tracked by wearable devices

The diverse database, which is a part of the Precision Medicine Initiative, is intended to inform studies on a multitude of heath conditions.

Precision medicine is individualized care that considers the environment, lifestyle, family health history, and genetic makeup of a patient. It acknowledges that certain treatments work differently for people with different backgrounds, treats patients as individuals, and can reduce health care costs by providing the right treatment the first time.