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Cold Spring Harbor Protocols is an interdisciplinary monthly journal of step-by-step research methods in cell, developmental and molecular biology, genetics, bioinformatics, protein science, computational biology, immunology, neuroscience and imaging. All protocols are up-to-date and presented in a consistent, easy-to-follow format.

Protocols is fully searchable by keyword and subject, and has several novel features including subject categories (including but not limited to antibodies, DNA delivery/gene transfer, electrophoresis, High-throughput analysis, imaging/microscopy, kits, laboratory organisms, plant biology, polymerase chain reaction (PCR), RNA interference (RNAi)/siRNA, and stem cells) as well as a full listing of “recipes” for preparing solutions and biological reagents.

June 2006 - present

Although there is no direct print counterpart, Cold Spring Harbor Protocols complements the seminal laboratory methods resource, Molecular Cloning: A Laboratory Manual, for which all  editions, spanning 30 years of established methods and techniques in molecular/cell biology research, are available in the Abbott Library.