AHRQ - AHRQ invests in research on the Nation's health delivery system that goes beyond the "what" of health care to understand "how" to make health care safer and improve quality. AHRQ creates materials to teach and train health care systems and professionals to put the results of research into practice. AHRQ generates measures and data used by providers and policymakers.

Alternatives to NGC see belowGuideline Central

Critical Appraisal Resources

PEDro - PEDro is the Physiotherapy Evidence Database, a free database of over 43,000 randomised trials, systematic reviews and clinical practice guidelines in physiotherapy. For each trial, review or guideline, PEDro provides the citation details, the abstract and a link to the full text, where possible. All trials on PEDro are independently assessed for quality. These quality ratings are used to quickly guide users to trials that are more likely to be valid and to contain sufficient information to guide clinical practice. PEDro is produced by the Institute for Musculoskeletal Health, School of Public Health at the University of Sydney and is hosted by Neuroscience Research Australia (NeuRA).

Joanna Briggs - List of Critical Appraisal tools for download

TRIP Database -  Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. https://www.tripdatabase.com/

National Guidelines Clearinghouse - no longer available

ECRI Institute Guidelines Trust - replaced NGC - interpret and contextualize clinical evidence in ways that inform decision making: ECRI is designated 1 of 13 Evidence-based Practice Centers by the U.S. Agency for Healthcare Research and Quality. https://www.ecri.org/

Guidelines Central - Guideline Central is dedicated to providing healthcare professionals with evidence-based clinical decision-support tools that are current, practical, and easily accessible. Read more at: https://www.guidelinecentral.com/about/  https://www.guidelinecentral.com/about/

ClinicalTrials.gov - ClinicalTrials.gov is a Web-based resource that provides patients, their family members, health care professionals, researchers, and the public with easy access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions. The Web site is maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH). Information on ClinicalTrials.gov is provided and updated by the sponsor or principal investigator of the clinical study. Studies are generally submitted to the Web site (that is, registered) when they begin, and the information on the site is updated throughout the study. In some cases, results of the study are submitted after the study ends. This Web site and database of clinical studies is commonly referred to as a "registry and results database."

ICSI Guidelines - ICSI has a rigorous process for developing and maintaining evidence-based guidelines and protocols.  https://www.icsi.org/guidelines/